Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF-κB Signaling
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چکیده
منابع مشابه
Hepatoprotective Effects of Curcumin Nanomicells in Alcohol-induced Liver Injury: Comparison with Curcumin and Silymarin in Mice Model
Background: Curcumin ameloriates liver damages but its poor absorption, rapid metabolism, and side effects at high doses may limit its clinical applications Objective: This study aimed to evaluate the protective and regenerative effects of Curcumin Nanomicells on alcohol-induced chronic liver injuries in mice. These effects were compared with Curcumin and Silymarin in the same model. Method...
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S-adenosyl-L-methionine (SAM) acts as a methyl donor for methylation reactions and participates in the synthesis of glutathione. SAM is also a key metabolite that regulates hepatocyte growth, differentiation and death. Hepatic SAM levels are decreased in animal models of alcohol liver injury and in patients with alcohol liver disease or viral cirrhosis. This review describes the protection by S...
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Objective(s): Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and antioxidant effects; however its role in aspiration induced ALI has not b...
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The aim of the present study was to explore the protective effect of small interfering RNA (siRNA) against nuclear factor κB (NF-κB) p65 on sepsis-induced acute lung injury (ALI) in mice. In total, 70 male Kunming mice were randomly divided into a healthy control group, a sepsis group, a specific interfering group and a scrambled control group (Sc), and the latter three groups were divided into...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2019
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2019/6029876